Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
| hla-compatible donor |
  |
|
| Attestation |
3
|
| Part of speech |
Noun syntagm
|
| Grammatical label |
Countable
|
| Variant |
Histocompatible donor
|
| Definition |
Stem cell or bone marrow donor whose HLA system is very similar to the one of the thalassemic patient undergoing transplantation. The donor can be related or unrelated (rarer match).
|
| Definition source |
Expert
|
| Context |
When a patients has an HLA-compatible donor, if transplantation is chosen, it should be done as soon as possible. However, in older patients at least, previous transfusion history is important - patients who received less than 100 transfusions before transplant having a higher probability of rejection - probably because a poorly suppressed bone marrow is more difficult to eradicate.
|
| Context source |
Cao, A., et al. (1997). Management Protocol for the treatment of Thalassemia patients. Nicosia: Thalassemia International Federation. (LISCEN01)
|
| Subject field |
Haemopoiesis
|
| Sub-field (level 1) |
Thalassemias
|
| Sub-field (level 2) |
Therapies
|
| Generic concept |
Bone marrow door, hematopoietic stem cell donor
|
| Specific concept |
Related donor, HLA-identical donor, unrelated donor
|
| Related concept |
Allogeneic bone marrow transplantation, HLA typing, HLA, hematopoietic stem cell transplantation, Graft-Versus-Host Disease
|
| it |
Donatore HLA-compatibile
|
| Reliability code |
3
|
|
