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Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
| myeloablation |
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| Attestation |
3
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| Part of speech |
Noun
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| Grammatical label |
Countable
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| Definition |
Action allowing the destruction of bone marrow activity. It is used to prepare patients for bone marrow or stem cell transplantation.
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| Definition source |
Cancerweb. OMD – On-line Medical Dictionary.
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| Context |
In murine models there is evidence of enhanced engraftment of donor stem cells, using TTP in the pre-transplant preparative regimen.21´23 This finding is attributed generally both to the reduction of stem cell competition through additional myeloablation and, recently, to the immunosuppressive properties of TTP.
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| Context source |
Nadkarni, A., et al. (2001). ‘Molecular pathogenesis and clinical variability of beta-thalassemia syndromes among Indians’. American Journal of Hematology 68(2):75-80. (RISCEN161)
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| Synonym |
Bone marrow ablation
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| Subject field |
Haemopoiesis
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| Sub-field (level 1) |
Thalassemias
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| Sub-field (level 2) |
Therapies
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| Generic concept |
Eradication
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| Related concept |
Allogeneic bone marrow transplantation, syngeneic bone marrow transplantation, hematopoietic stem cell transplantation, marrow cavity, bone marrow space, total body irradiation, conditioning regimen, mixed chimerism
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| it |
Mieloablazione
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| Reliability code |
3
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