Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
| English |
| chemotherapeutic agents |
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| Attestation |
3
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| Definition |
Chemotherapeutic agents are those medications that are used to treat various forms of cancer. These medications are given in a particular regimen over a period of weeks. Most chemotherapeutic medications have the ability to directly kill cancer cells. For this same reason, these medications can suppress the bone marrow to some degree, lowering white blood cell counts. This results in a condition known as immunosuppression and can place the patient at an increased risk of infection. Examples include busulphan, cisplatin, cyclophosphamide, methotrexate, daunorubicin, doxorubicin, melphalan, vincristine, vinblastine and chlorambucil.
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| Definition source |
http://www.graylab.ac.uk/cgi-bin/omd?chemotherapeutic+agent
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| Context |
A second prediction from the hypothesis that ALL arises in cells that are poised to die is that the normal progenitor cells from which these leukemias arise will also be easily killed by the same chemotherapeutic agents. In fact, the lympholytic nature of corticosteroids has long been known; and other potent chemotherapeutic agents, eg, the antimetabolites, have significant effects on the lymphoid system and are often used as immunosuppressive agents.
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| Context source |
en02
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| Synonym |
chemotherapeutic drugs; chemotherapeutics.
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| Subject field |
Pediatric Oncohematology
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| de |
Chemotherapeutika
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| it |
chemioterapici
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| Reliability code |
3
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