Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
| English |
| immunosuppression |
  |
|
| Attestation |
3
|
| Variant |
A
|
| Definition |
Lowering the immune response, for example, with radiation or medications.
A state in which the immune system does not function properly and its protective functions are inadequate. The patient is more susceptible infections, including from microbes that are usually not highly infectious (See Opportunistic Infection). This can occur as a result of intensive chemotherapy and radiation therapy, especially as used for conditioning of a patient for transplantation. It also can occur because of disease states. Human immunodeficiency virus infection can lead to immunosuppression. Graft versus host disease creates an immunosuppressive state in that immune protection against infection is inadequate. In the transplant patient, the conditioning regimen and severe graft versus host disease can combine to permit overwhelming infection.
|
| Definition source |
http://www.medterms.com/script/main/art.asp?articlekey=3942&rd=1
http://www.leukemia.org/all_glossary.adp
|
| Context |
Severe leukopenia and thrombocytopenia; immunosuppression, nausea, vomiting, anorexia, stomatitis, GI ulceration, fever, alopecia, and rash; cerebellar toxicity and ataxia also may develop.
|
| Context source |
en34
|
| Figure source |
http://www.nlm.nih.gov/medlineplus/ency/imagepage/8932.htm
|
| Subject field |
Pediatric Oncohematology
|
| de |
Immunsuppression
|
| it |
immunosoppressione
|
| Reliability code |
3
|
|
