| English |
| megakaryocytopoiesis |
  |
|
| Attestation |
3
|
| Part of speech |
Noun
|
| Grammatical label |
Countable
|
| Definition |
The proliferation and maturation of megakaryocytes (giant polyploid cell of bone marrow that gives rise to 3-4,000 platelets).
|
| Definition source |
Cancerweb. OMD – On-line Medical Dictionary.
|
| Context |
All babies with thrombocytopenia due to placental insufficiency have been shown to have reduced numbers of circulating megakaryocytes and their progenitor cells (BFU-MK and CFU-MK). They also have elevated levels of thrombopoietin at birth consistent with a true reduction in megakaryocytopoiesis rather than a selective absence in circulating megakaryocyte progenitors. In the majority of cases the inhibition of megakaryocytopoiesis is severe.
|
| Context source |
Ma, ES., et al. (2001). ‘Interaction between (--SEA) alpha-thalassemia deletion and uncommon non-deletional alpha-globin gene mutations in Chinese patients’. Haematologica. 86(5):539-40. (RISCEN25)
|
| Subject field |
Haemopoiesis
|
| Generic concept |
Lymphocytopoiesis, haemopoiesis
|
| Coordinate concept |
Erythropoiesis
|
| Related concept |
Anemia, erythron, erythrocyte, lymphocyte, granulocyte, monocyte, platelet
|
| it |
Megacariocitopoiesi
|
| Reliability code |
3
|
