| English |
| syngeneic bone marrow transplantation |
  |
|
| Attestation |
2
|
| Part of speech |
Noun syntagm
|
| Grammatical label |
Countable
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| Variant |
Syngeneic transplantation, syngeneic marrow transplantation, syngeneic BMT
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| Definition |
In syngeneic transplantation, bone marrow is taken from an identical twin. Different people usually have different sets of proteins, called human leukocyte-associated (HLA) antigens, on the surface of their cells that allow white blood cells to distinguish the body´s own cells from those of another person. However, because identical twins have the same genes, they also have the same set of HLA antigens (they are said to be a perfect HLA match). As a result, the patient´s body usually accepts the graft (transplant). Given that identical twins represent only 0.3 percent of all births (1 birth out of every 270), syngeneic transplantation is rare.
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| Definition source |
Universität Göttingen. Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation. (INTEEN04)
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| Context |
Syngeneic transplantation is a procedure in which a patient receives bone marrow from a genetically identical individual (identical twin).
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| Context source |
Universität Göttingen. Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation. (INTEEN04)
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| Subject field |
Haemopoiesis
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| Sub-field (level 1) |
Thalassemias
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| Sub-field (level 2) |
Therapies
|
| Generic concept |
Hematopoietic stem cell transplantation, in utero stem cell transplantation
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| Coordinate concept |
Allogeneic bone marrow transplantation, autologous bone marrow transplantation
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| it |
Trapianto di midollo osseo singenico
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| Reliability code |
3
|
