| English |
| umbilical cord blood |
  |
|
| Attestation |
3
|
| Part of speech |
Noun syntagm
|
| Grammatical label |
Uncountable
|
| Definition |
Several hospitals are currently developing a umbilical cord-blood bank. Blood donated from the placenta of the new born infant contains large numbers of stem cells that can be used for bone marrow transplantation. Early research indicates that these young stem cells are more likely to engraft in a recipient and do not necessarily have to be HLA-identical. Research is currently under way to increase the numbers of stem cells in cord blood after it is collected. In addition, perpherial blood contains stem cells; using pheresis techniques, these cells can be sorted and collected for transplantation. The same research which may lead to increasing the numbers of stem cells in cord blood can be used on perpherial blood stem cells. This is the hope for the future of transplantation.
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| Definition source |
Children’s Hospital Oakland. Medical Section. (INDIEN01)
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| Context |
A sample of 95 ml umbilical cord blood was taken during the delivery. It is well known that umbilical cord blood contains a good quantity of CD34+ stem cells, the haematopoietic progenitors. It was therefore collected for transplanting to the mother and for bone marrow reconstitution.
|
| Context source |
Pafumi, C., et al. (2000). ‘Pregnancy outcome of a transfusion-dependent thalassemic woman’. Annals of Hematology 79(10):571-3. (RISCEN87)
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| Subject field |
Haemopoiesis
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| Sub-field (level 1) |
Thalassemias
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| Sub-field (level 2) |
Therapies
|
| Coordinate concept |
Bone marrow, fetal liver
|
| it |
Sangue di cordone ombelicale
|
| Reliability code |
3
|
