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Further evidence of its validity comes from the observation of its susceptibility to decline with brain damage. When speaking of brain disease, one may be tempted to think of something akin to an inflammation, but DISEASE is a broad term that carries no particular implication for the etiology of the diseased or abnormal state. Brain disease may be acquired through such mechanisms as heredity, brain tumors, prenatal trauma or metabolic disorders, postnatal vascular events such as stroke, a shearing of the brain from sudden rotation, and missile wounds such as from a gunshot.
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