Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
| hemochromatosis |
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| Attestation |
3
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| Part of speech |
Noun
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| Grammatical label |
Uncountable
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| Definition |
Guidance about the risk of complications associated with slightly higher levels of body iron may be derived from the clinical experience with hemochromatosis, a condition in which the route and severity of iron loading may be similar to those in thalassemia intermedia. In both these conditions, iron overload is the result of abnormal regulation of iron absorption resulting in an inappropriate increase in iron uptake. The minor degree of iron loading that develops in about one-quarter of patients who are heterozygotic for hereditary hemochromatosis appears to be associated with normal life expectancy.
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| Definition source |
AA.VV. (1997). ‘Thalassemia Intermedia. A Region I Conference’. The Genetic Resource Special Issue, 1997, Volume 11, Number 2 (COSCEN01)
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| Context |
Nevertheless, cardiac hemochromatosis can develop in young thalassemic polytransfused adults with high ferritin levels.
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| Context source |
Lombardo, T., et al. (1995). ‘Cardiac iron overload in thalassemic patients: an endomyocardial biopsy study’. Annals of Hematology 71(3):135-41. (RISCEN94)
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| Synonym |
Hereditary hemochromatosis, acquired hemochromatosis
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| Subject field |
Haemopoiesis
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| Sub-field (level 1) |
Thalassemias
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| Sub-field (level 2) |
Therapies
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| Generic concept |
Iron overload
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| Coordinate concept |
Hemosiderosis
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| Related concept |
Hepatosplenomegaly, iron-chelation therapy, chelation, iron-chelating agent, hemoglobin, liver siderosis
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| it |
Emocromatosi
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| Reliability code |
3
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