Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
| English |
| prognostic factors |
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| Attestation |
3
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| Definition |
The most important part of the laboratory testing for leukemia focuses on determining the type of leukemia the child has and what the prognostic factors are.This will determine which treatments will work best. Certain consistently observed differences among patients with good and poor responses to treatment are considered of prognostic importance. Prognostic factors are important in dividing children into risk categories/groups (SR, MR, HR) and decide whether a child with leukemia should receive standard or more intensive treatment. The most important prognostic factors in childhood ALL are WBC count, age, sex, immunophenotype, cytogenetics and molecular genetics, extramedullary leukemia (CNS and testis), morphology, drug resistance, response to treatment, MRD.
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| Definition source |
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| Context |
The identification of clinical and biological prognostic factors associated with ALL has resulted in the formation of subsets of patients classified into risk groups. Although age, initial white blood cell count, and central nervous system or testicular disease are all important prognostic factors, cytogenetic abnormalities have now emerged as the single most important prognostic factor for children with ALL.
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| Context source |
en30
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| Synonym |
prognostic variables, predictive factors, risk factors.
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| Subject field |
Pediatric Oncohematology
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| de |
prognostischeFaktoren
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| it |
fattori prognostici
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| Reliability code |
3
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