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previous hd- - collezione «Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta» - Federica Bordoni next
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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta

English
hd- clicca per ingrandire
Attestation 3
Variant high-dose
Definition High dose, referring to chemotherapeutic agents. Patients who receive high-dose chemotherapy are at great risk of suffering life-threatening side effects because the treatment damages their bone marrow and they no longer are able to produce needed blood cells. To help repair the damage done by high doses of drugs, the treatment includes peripheral blood stem cell transplantation and/or bone marrow transplantation.
Definition source fb
Context With regard to late effects of HD-MTX, a critical comparison between patients treated with chemoprophylaxis based on intensive use of intravenous MTX and intrathecal MTX (or triple intrathecal therapy) and patients treated with preventive radiotherapy, or combinations of both treatments, is needed because it is still not known which regimen is less toxic in the long term.
Context source en07
Subject field Pediatric Oncohematology
Related concept high-dose chemotherapy
de HD-
it HD-
Reliability code 3



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