Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
| English |
| cytarabine |
  |
|
| Attestation |
3
|
| Definition |
a cytotoxic antineoplastic agent C9H13N3O5 that is a synthetic isomer of the naturally occurring nucleoside of cytosine and arabinose and is used especially in the treatment of acute leukemias.
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| Definition source |
Merriam-Webster´s Medical Dictionary
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| Context |
Of considerable therapeutic interest, the leukemiccells of infants with ALL are significantly more sensitiveto cytarabine than are cells from older children.132 In addition, B-cell precursors that lacked CD10 expression were resistant to prednisone and L-asparaginase but showed significant sensitivity to cytarabine, in contrast to cases with CD10 expression.
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| Context source |
en04
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| Synonym |
Ara-C, cytosine arabinoside, cytarabine, arabinosyl cytosine.
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| Subject field |
Pediatric Oncohematology
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| Generic concept |
antimetabolites
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| de |
AraC
|
| it |
ARA-C
|
| Reliability code |
3
|
|
