Hemodialysis: A medical procedure that uses a special machine (a dialysis machine) to filter waste products from the bloodstream and to restore normal constituents to the blood. This remarkable feat shuffling multiple substances about is accomplished by virtue of the differences in the rates of their diffusion through a semipermeable membrane (a dialysis membrane). Although hemodialysis may be done for acute, it is much more often employed for chronic renal disease. Hemodialysis is frequently done to treat end-stage kidney disease. Under such circumstances, kidney dialysis is typically administered using a fixed schedule of three times per week.
If it is accepted that hemodialysis therapy for end-stage renal disease (ESRD) still requires an empirical approach, even after 30 years of experience, it is clear that the proof of clinical relevance of biochemical changes occurring as the consequence of blood-dialyzers interaction will continue to remain controversial