Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
| osteoporosis |
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| Attestation |
3
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| Part of speech |
Noun
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| Grammatical label |
Countable
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| Definition |
Osteoporosis is a common and important complication in older thalassaemics, that is not obviously related to iron overload. It often becomes symptomatic in the late twenties, but starts much earlier. Diagnosis is by bone densitometry over the spine and hip. Osteoporosis seems to be related to many interacting factors: the following need to be considered in every case.
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| Definition source |
Cao, A., et al. (1997). Management Protocol for the treatment of Thalassemia patients. Nicosia: Thalassemia International Federation. (LISCEN01)
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| Context |
At this moment pale, subicteric, liver swells 2 cm beyond costal margin. X-ray examination shows diffuse osteoporosis, microareolar thickening of cranial diploe but no heterotopic bone marrow masses.
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| Context source |
Bianco Silvestroni, I., et al. (1997). ‘Phenotypes of individuals with a beta thal classical allele associated either with a beta thal silent allele or with alpha globin gene triplication’. Haematologica 82(5):513-25. (RISCEN53)
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| Subject field |
Haemopoiesis
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| Sub-field (level 1) |
Thalassemias
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| Generic concept |
Bone demineralization
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| Coordinate concept |
Osteopenia
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| it |
Osteoporosi
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| Reliability code |
3
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