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| previous | globin - collezione «Medicina: Ematologia: Talassemie e trapianto del midollo osseo» - Deborah Olmi | next |
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Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
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| 3 |
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| Noun |
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| Countable |
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| The polypeptide moiety of hemoglobin. In the adult human the hemoglobin molecule has two a (141 residues) and two non-a (146 residues) globin chains. |
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| Cancerweb. OMD – On-line Medical Dictionary. |
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| Homozygosity or double heterozygosity for b-thalassemia results usually in a very severe anemia due to ineffective erythropoiesis and hemolysis, in which the pathology is caused by the lack of functional hemoglobin tetramers and by the large amount of free unstable a-globin chains. |
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| Giordano, PC., et al. (1998). ‘Phenotype variability of the dominant beta-thalassemia induced in four Dutch families by the rare cd121 (G-->T) mutation’. Annals of Hematology 77(6):249-55. (RISCEN92) |
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| Globin chain |
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| Haemopoiesis |
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| a globin, b globin, d globin, g globin, e globin, z globin |
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| Globina |
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| 3 |
