| English |
| monoclonal antibody |
  |
|
| Attestation |
3
|
| Part of speech |
Noun syntagm
|
| Grammatical label |
Countable
|
| Definition |
Laboratory-produced identical antibodies that can target a specific antigen. They can be made in large quantities in the laboratory and are being studied to determine their effectiveness in the detection and treatment of cancer. Monoclonal antibodies are used to destroy specialized bone marrow cells in the donor´s marrow that might otherwise hurt the transplant recipient. They allow less perfectly matched donor marrow to be used. Cell and gene therapy for inherited disorders and for malignant diseases are being combined with marrow transplantation to increase the effectiveness of the process.
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| Definition source |
St. Jude Children’s Research Hospital. Bone Marrow Transplant. (INTEEN06)
|
| Context |
Evaluation of the distribution of different circulating lymphocyte subsets was performed on whole blood aliquots by direct immunofluorescent staining with fluorochrome-conjugated monoclonal antibodies specific for leukocyte surface markers, and multiparameter analysis by flow cytometry with a FACScan cytometer.
|
| Context source |
Madan, N., et al. (1996). ‘Serum ferritin levels in carriers of beta-thalassaemia trait’. Acta Haematologica 96(4):267. (RISCEN151)
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| Subject field |
Haemopoiesis
|
| Sub-field (level 1) |
Thalassemias
|
| Sub-field (level 2) |
Therapies
|
| Generic concept |
Antibody
|
| it |
Anticorpo monoclonale
|
| Reliability code |
3
|
