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| previous | globin synthesis imbalance - collezione «Medicina: Ematologia: Talassemie e trapianto del midollo osseo» - Deborah Olmi | next |
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Medicina: Ematologia: Talassemie e trapianto del midollo osseo
| English |
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| 3 |
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| Noun syntagm |
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| Countable |
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| Globin chain synthesis imbalance |
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| Thalassemias are a diverse group of inherited disorders in which the rate of production of certain hemoglobins is decreased leading to an imbalance of globin chains available for hemoglobin dimer construction. This results in the formation of abnormal amounts of structurally normal (normal amino acid sequence) hemoglobins. For instance, if inadequate numbers of b-chains were synthesized, a-chains would be in relative excess and would precipitate. |
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| University of Virginia. Red Cell Disorders – Thalassemia. (INTEEN07) |
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| Any inherited or acquired factor able to reduce the globin chain imbalance may thereby result in a milder form of thalassemia. |
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| Cao, A., et al. (1994). ‘Genotype-phenoptype correlations in beta-thalassemias’. Blood Reviews 8(1):1-12. Review. (RISCEN85) |
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| Haemopoiesis |
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| Thalassemias |
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| Precipitation, microcythemia |
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| Squilibrio globinosintetico |
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| 3 |
