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| previous | bilineage leukemia - collezione «Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta» - Federica Bordoni | next |
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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
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| 3 |
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| When single blasts express lymphoid or myeloid antigens but not both, these leukemias are regarded as bilineage. |
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| http://www.haematologica.it/full/pdf/2000_10/851083.pdf |
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| We report here a case of a true bilineage leukemia in a child associated with arrangement of the MLL gene. The morphologic findings showed two distinct blast populations, one small and lymphoid appearing, with a minor population showing irregular nuclei and a low N/C ratio. This morphologic dichotomy was reflected in the flow results in which there were two different populations, one of B-cell precursor lymphoid immunophenotype CD19+CD10-CD22+CD15+CD33-CD13-, and the other CD19-CD10-CD22-CD33+CD14+/-CD64+CD13+, consistent with myeloid leukemia with monocytic differentiation. |
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| http://www.flowcases.org/casebuilder/index.cfm?fuseaction=displayCase2&caseID=8 |
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| Pediatric Oncohematology |
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| acute leukemia |
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| biklonale Leukämie |
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| LAB |
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| 3 |
