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| previous | tumor lysis syndrome - collezione «Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta» - Federica Bordoni | next |
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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
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| Rapid destruction of cancer cells can result in the release of cellular breakdown products such is Uric Acid, Potassium, Phosphorous, Acidic ions, etc. . Death of cancer cells could be natural or secondary to chemotherapy. Alternatively, chemotherapy can induce this syndrome in patients whose cancers are very sensitive to treatment e.g. Leukemias , as well as small cell lung cancer and breast cancer. Uric acid and Calcium Phosphate can precipitate in kidneys and cause kidney failure. |
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| http://www.tirgan.com/tumolys.htm |
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| Prior to and during the initial induction phase of chemotherapy, patients may develop tumor lysis syndrome. This syndrome refers to the metabolic derangements caused by the systemic and rapid release of intracellular contents as the leukemic blasts are destroyed by chemotherapy. Because some cells can die prior to therapy, such derangements can occur even before therapy begins. |
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| http://www.emedicine.com/ped/topic2587.htm |
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| Pediatric Oncohematology |
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| Tumor-Lyse-Syndrom |
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| sindrome da lisi tumorale massiva |
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