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| previous | alkylating agents - collezione «Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta» - Federica Bordoni | next |
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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
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| alkalating agents |
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| Drugs that interact with and injure DNA in such a way as to prevent cells growth. Drugs of this type include mechlorethamine, chlorambucil, cyclophosphamide, melphalan, carmustine, and others. They are used principally to treat cancers of lymphocytes such as chronic lymphocytic leukemia, lymphomas, and myeloma. Nitrogen mustard was the first alkylating agent and first chemotherapeutic drug applied to cancer therapy at the end of World War II. It has now been largely supplanted by other alkylating agents. |
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| http://www.leukemia-lymphoma.org/all_glossary.adp?item_id=9286 |
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| Another treatment approach for decreasing late effects of therapy utilizes anthracyclines and alkylating agents, but limits their cumulative dose to an amount not associated with substantial long-term toxicity. |
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| en32 |
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| alkalysing agents |
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| Pediatric Oncohematology |
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| antineoplastic drugs |
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| cyclophosphamide, ifosfamide. |
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| Alkylantien |
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| alchilanti |
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| 3 |
