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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta

English
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Attestation 3
Definition Event-free survival (EFS) is defined as the time from study entry to the first major event (failure to achieve remission, relapse at any site, resistant leukemia, early death or death from any cause, tumor progression or second malignancy) or last follow up.
Definition source http://www.leukemia-lymphoma.org/all_glossary.adptop
Context The following variables were adversely associated with EFS: age under 1 year, age over 10 years, WBC count higher than 50 × 109L, hepatomegaly and splenomegaly, BFM-RF 1.7 or higher, mediastinal mass, CNS involvement, pro-B-cell ALL, T-ALL, t(9;22), t(4;11), nonresponse at day 33, and PPR. In contrast, the following variables were associated with a more favorable EFS: female sex, age 1 to 5 years, WBC count below 10 × 109L, BFM-RF below 0.8, hemoglobin value below 80 g/L, common ALL, DNA index 1.16 or higher, and PGR.
Context source en07
Subject field Pediatric Oncohematology
Generic concept Überleben
de EFS
it EFS
Reliability code 3



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