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| previous | neutropenia (en) - collezione «Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta» - Federica Bordoni | next |
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Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
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| Shortage of neutrophils. A marked decrease in the number of neutrophils, a type of white blood cell filled with microscopic granules that are little sacs containing enzymes, compounds that digest microorganisms. Neutrophils are a kind of granulocytes. Granulocytes are part of the innate immune system and have somewhat nonspecific, broad-based activity. They do not respond exclusively to specific antigens, as do B-cells and T-cells.Granulocytopenia or, as it is also called, agranulocytosis results in a syndrome of frequent chronic bacterial infections of the skin, lungs, etc. Although "agranulocytosis" literally means no granulocytes, there may, in fact, be some granulocytes but too few of them, i.e. granulocytopenia. Granulocytopenia can be genetic and inherited or it can be acquired as, for example, an aspect of leukemia . |
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| http://www.medterms.com/script/main/art.asp?articlekey=4560&rd=1 |
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| An increase of neutropenia and thrombocytopenia episodes was observed in the HD- ASP arm; this information suggests that ASP added at high doses may increase the hematologic toxicity of an intensive chemotherapy schedule even in the absence of effective asparagine depletion. |
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| en12 |
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| neutrophilopenia |
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| Pediatric Oncohematology |
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| leukopenia,granulocytopenia |
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| Neutropenie |
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| neutropenia |
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| The term neutropenia is mostly used interchangeably with granulocytopenia within this domain, although this is not precise, since neutrophils are one type of granulocytes. |
