the event-free interval (EFI) is calculated from the time of randomization to the end of the first remission (relapse, death in CCR, or second malignancy) or to the time of analysis.
EFS was 85% ± 2% in the SRG (n = 636) and 82% ± 1% in the MRG (n = 1299). L-asparaginase did not improve outcome in the MRG: the EFI was 83% ± 2% with L-asparaginase (n = 528) and 81% ± 2% without it (n =557).