SR criteria were: WBC countless than 10 000/mm;, age comprised between 3 and less than 7 years, non-T immunophenotype , no ´leukemia-lymphoma syndrome´ (LLS, defined as the presenceof massive splenomegaly, or massive adenopathy, or mediastinal mass + one or more laboratory findings including:T-immunophenotype, Hb >10 g/dl, WBC %50 000/mm3), FAB morphology L1.