Context |
The following variables were adversely associated with EFS: age under 1 year, age over 10 years, WBC count higher than 50 × 109L, hepatomegaly and splenomegaly, BFM-RF 1.7 or higher, mediastinal mass, CNS involvement, pro-B-cell ALL, T-ALL, t(9;22), t(4;11), nonresponse at day 33, and PPR. In contrast, the following variables were associated with a more favorable EFS: female sex, age 1 to 5 years, WBC count below 10 × 109L, BFM-RF below 0.8, hemoglobin value below 80 g/L, common ALL, DNA index 1.16 or higher, and PGR.
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