Medicina: Oncoematologia pediatrica: Leucemia linfoblastica acuta
| English |
| anthracyclines |
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| Attestation |
3
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| Definition |
Drugs derived from microorganisms, especially fungithat prevent cell division by disrupting the structure of DNA. Drugs of this type include daunorubicin, doxorubicin, epirubicin, and idarubicin. These drugs are used in the treatment of acute leukemia, lymphomas, and myeloma.
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| Definition source |
http://www.leukemia.org/all_glossary.adp
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| Context |
For patients at high risk for treatment failure, a more intense induction regimen (4 or 5 agents) may result in improved event-free survival, 3-5 and “high risk” patients generally receive induction therapy that includes an anthracycline (e.g., daunomycin) in addition to vincristine, prednisone/dexamethasone, plus L-asparaginase. For patients who are at standard or low risk of treatment failure, the addition of an anthracycline to 3-drug induction therapy does not appear necessary for favorable outcome provided that adequate postremission intensification therapy is administered.
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| Context source |
en32
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| Synonym |
anthracycline antibiotics
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| Subject field |
Pediatric Oncohematology
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| Generic concept |
antineoplastic drugs
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| Specific concept |
adriamycin, daunorubicin,
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| de |
Anthrazyklinen
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| it |
antracicline
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| Reliability code |
3
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