Definition |
Major system for the control of extracellular fluid volume by regulating aldosterone secretion. The enzyme renin is released from the justaglomerular cells of the kidney and increases the production of angiotensin I from its substrate. Angiotensin is rapidly converted into the biologically active angiotensin II, which increases aldosterone secretion. Angiotensin II also produces vasocostriction, thereby raising blood pressure and reducing blood flow to a variety of tissues, especially the kidney.
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