| English |
| alpha1 blockers |
  |
|
| Part of speech |
n.p.pl.
|
| Definition |
Drugs that act by blocking or inhibiting the postsynaptic alpha1 receptors on vascular smooth muscle. This inhibit the uptake of catecholamines by smooth muscle cells. Vasoconstriction is blunted, and peripheral vasodilation occurs.
|
| Definition source |
(33)
|
| Context |
Several trials have demonstrated that alpha1 blockers may have a favourable effect on lipid levels and reduce plasma insuline levels and improve glucose tolerance. Because of these possible advantages, it has been suggested that alpha1 blockers may be ideal antihypertensive agents.
|
| Context source |
(33)
|
| Synonym |
alpha1 adrenergic inhibitors, adrenoceptor blockers
|
| Subject field |
Cardiology
|
| Related concept |
selective/non selective blockers, central acting alpha1 inhibitors, combined and blockers
|
| it |
ALFA1 BLOCCANTI
|
