The term Chronic renal failure (CRF) is traditionally used to describe renal insufficiency that develops over months or years CRF is permanent, usually progressive, diminution in renal function to a degree that has damaging consequences for the patient. This occurs when glomerular filtration rate (GFR) is reduced by at least 50 mL/min.
Healthy volunteers and patients with chronic renal failure showed no statistical differences in concentration of TNF-alpha and IL-6 before and after whole blood stimulation (WBS)