Hemodiafiltration (HDF) is a diffusive convective technique with a better extraction of high molecular weight solutes than hemodialysis (HD) and of low molecular weight solutes than hemofiltration (HF) Hemodiafiltration broadens the spectrum of removal while maintaining higher small molecule clearances Hemodiafiltration (HDF) refers to a combination of dialysis and filtration. Solute is removed primarily by diffusion dialysis, but 25% or more may be removed by convection Hemodiafiltration (HDF) enhances convective clearances through highly permeable membranes and offers the highest solute flux per membrane surface area for solutes of both low and medium molecular weights
Analysis ran from the time when the lactate-free dialysate was introduced to the time when the modality of renal replacement used was changed for hemodiafiltration to hemofiltration as a result of the introduction of new CRRT technology